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Recombinant TWIST1 抗体 (AA 1-50)

This anti-TWIST1 antibody is a 兔 单克隆 antibody detecting TWIST1 in WB, IP 和 ICC. Suitable for 人.
产品编号 ABIN7453340
发货至: 中国

Quick Overview for Recombinant TWIST1 抗体 (AA 1-50) (ABIN7453340)

抗原

See all TWIST1 抗体
TWIST1 (Twist Homolog 1 (Drosophila) (TWIST1))

抗体类型

Recombinant Antibody

适用

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宿主

  • 32
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克隆类型

  • 34
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单克隆

标记

  • 51
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This TWIST1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC)

克隆位点

BLR156J
  • 抗原表位

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    AA 1-50

    原理

    Rabbit anti-TWIST Recombinant Monoclonal Antibody [BLR156J]

    免疫原

    between AA 1 and 50

    亚型

    IgG
  • 应用备注

    IP: 20 μL/1 mg lysate

    ICC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.

    WB: 01:01,00

    限制

    仅限研究用
  • 浓度

    250 μg/mL

    缓冲液

    Phosphate Buffered Saline (PBS) containing 0.2 % BSA and 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    TWIST1 (Twist Homolog 1 (Drosophila) (TWIST1))

    别名

    TWIST1

    背景

    Background: TWIST1 is a basic helix-loop-helix (bHLH) transcription factor that plays an important role in embryonic development. TWIST1 forms both homodimers and heterodimers that bind to DNA E box sequences and regulate the transcription of genes involved in cranial suture closure during skull development. TWIST1 may also regulate neural tube closure, limb development and brown fat metabolism. The TWIST1 gene is hypermethylated and overexpressed in multiple human cancers, and the encoded protein promotes tumor cell invasion and metastasis, as well as metastatic recurrence. [taken from NCBI Entrez Gene (Gene ID: 7291)].

    基因ID

    7291

    NCBI登录号

    NP_000465

    UniProt

    Q15672

    途径

    p53 Pathway, Proton Transport, Tube Formation, Negative Regulation of Transporter Activity
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