Recombinant TWIST1 抗体 (AA 1-50)
Quick Overview for Recombinant TWIST1 抗体 (AA 1-50) (ABIN7453340)
抗原
See all TWIST1 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-50
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原理
- Rabbit anti-TWIST Recombinant Monoclonal Antibody [BLR156J]
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免疫原
- between AA 1 and 50
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亚型
- IgG
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应用备注
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IP: 20 μL/1 mg lysate
ICC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.
WB: 01:01,00
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限制
- 仅限研究用
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浓度
- 250 μg/mL
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缓冲液
- Phosphate Buffered Saline (PBS) containing 0.2 % BSA and 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- TWIST1 (Twist Homolog 1 (Drosophila) (TWIST1))
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别名
- TWIST1
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背景
- Background: TWIST1 is a basic helix-loop-helix (bHLH) transcription factor that plays an important role in embryonic development. TWIST1 forms both homodimers and heterodimers that bind to DNA E box sequences and regulate the transcription of genes involved in cranial suture closure during skull development. TWIST1 may also regulate neural tube closure, limb development and brown fat metabolism. The TWIST1 gene is hypermethylated and overexpressed in multiple human cancers, and the encoded protein promotes tumor cell invasion and metastasis, as well as metastatic recurrence. [taken from NCBI Entrez Gene (Gene ID: 7291)].
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基因ID
- 7291
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NCBI登录号
- NP_000465
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UniProt
- Q15672
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途径
- p53 Pathway, Proton Transport, Tube Formation, Negative Regulation of Transporter Activity
抗原
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