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Recombinant ZEB1 抗体 (AA 1074-1124)

This anti-ZEB1 antibody is a 兔 单克隆 antibody detecting ZEB1 in WB 和 IP. Suitable for 人 和 小鼠.
产品编号 ABIN7453320
发货至: 中国

Quick Overview for Recombinant ZEB1 抗体 (AA 1074-1124) (ABIN7453320)

抗原

See all ZEB1 抗体
ZEB1 (Zinc Finger E-Box Binding Homeobox 1 (ZEB1))

抗体类型

Recombinant Antibody

适用

  • 46
  • 14
  • 9
  • 7
  • 5
  • 4
  • 4
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
人, 小鼠

宿主

  • 33
  • 14
  • 1

克隆类型

  • 30
  • 18
单克隆

标记

  • 44
  • 2
  • 1
  • 1
This ZEB1 antibody is un-conjugated

应用范围

  • 39
  • 20
  • 18
  • 18
  • 11
  • 10
  • 7
  • 5
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunoprecipitation (IP)

克隆位点

BLR102H
  • 抗原表位

    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1074-1124

    原理

    Rabbit anti-ZEB1 Recombinant Monoclonal Antibody [BLR102H]

    免疫原

    between AA 1074 and 1124 (C-term)

    亚型

    IgG
  • 应用备注

    IP: 20 μL/1 mg lysate

    WB: 01:01,00

    限制

    仅限研究用
  • 浓度

    100 μg/mL

    缓冲液

    Borate Buffered Saline (BBS) pH 8.2 with 0.1 % BSA and 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    ZEB1 (Zinc Finger E-Box Binding Homeobox 1 (ZEB1))

    别名

    ZEB1

    背景

    Background: ZEB1 (zinc-finger E-box-binding homeobox 1), also known as TCF8 (transcription factor 8), is a delta-EF1/ZFH-1 C2H2-type zinc finger that bears seven C2H2-type zinc fingers and one homeobox DNA-binding domain. ZEB1 is a transcriptional repressor of interleukin-2 (IL-2). Mutations in the ZEB1 gene are associated with posterior corneal dystrophy type 3 (PPC3) a rare disorder characterized by metaplasia and overgrowth of corneal endothelial cells. ZEB1 appears to be critical to epithelial to mesenchymal transitions (EMT) during development and cancer metastasis. As a transcription factor involved in EMT, ZEB1 promotes EMT by repressing genes associated with the epithelial phenotype and activates genes associated with the mesenchymal phenotype.

    基因ID

    6935

    NCBI登录号

    NP_110378

    UniProt

    P37275

    途径

    Regulation of Muscle Cell Differentiation
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