IDE 抗体 (AA 275-326)
Quick Overview for IDE 抗体 (AA 275-326) (ABIN7453106)
抗原
See all IDE 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 275-326
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原理
- Rabbit anti-IDE Antibody, Affinity Purified
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预测反应
- Mouse,Rat,Bovine
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纯化方法
- Affinity Purified
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免疫原
- between AA 275 and 326
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亚型
- IgG
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应用备注
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IP: Not recommended
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- IDE (Insulin-Degrading Enzyme (IDE))
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别名
- IDE
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背景
- Background: Insulin-degrading enzyme (IDE) is a metalloendopeptidase that plays a primary role in the regulated degradation of insulin. In the cell, IDE is found mostly in the soluble cytosolic fraction, and small amounts exist in the plasma membrane, endosomes, and peroxisomes, however the highest relative concentration is found in the peroxisomes. IDE is proposed to be a multifunctional enzyme since it is also present in non-insulin sensitive cells. Other substrates of IDE include glucagon, IGF-II, atrial natriuretic factor, and TGF-alpha.
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基因ID
- 3416
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NCBI登录号
- NP_004960
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UniProt
- P14735
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途径
- SARS-CoV-2 Protein Interactome
抗原
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