VSX2 抗体 (AA 251-361)
Quick Overview for VSX2 抗体 (AA 251-361) (ABIN718976)
抗原
See all VSX2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 251-361
-
交叉反应
- 人, 小鼠
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated synthetic peptide derived from human CHX10
-
亚型
- IgG
-
-
-
-
应用备注
-
WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
-
有效期
- 12 months
-
-
- VSX2 (Visual System Homeobox 2 (VSX2))
-
别名
- CHX10
-
背景
-
Synonyms: C elegans ceh 10 homeo domain containing homolog, Ceh 10 homeo domain containing homolog C. elegans, Ceh 10 homeo domain containing homolog, Ceh 10 homeodomain containing homolog, Ceh 10 homeodomain containing homolog C. elegans, Ceh10 homeo domain containing homolog, Ceh10 homeodomain containing homolog, CHX 10, Homeobox protein CHX 10, Homeobox protein CHX10, HOX 10, HOX10, MCOP 2, MCOP2, MCOPCB 3, MCOPCB3, RET 1, RET1, Vsx 2, Vsx2.
Background: CHX10 is a 40 kDa homeodomain protein of the paired-like class that is essential for development of the mammalian eye. Mutations in CHX10 cause microphthalmia, a cause of congenital blindness in humans, and the ocular retardation (or) phenotype in mice. In the developing mouse retina CHX10 is expressed in retinal progenitors, while in the mature retina, CHX10 expression becomes restricted to bipolar neurons. Concurrent with these expression patterns, the CHX10-/- (or) retina is thin due to a defect in proliferation of retinal progenitors, and lacks bipolar neurons. CHX10 is also expressed in the developing brainstem, thalamus, and spinal cord.
-
基因ID
- 338917
-
途径
- Dopaminergic Neurogenesis
抗原
-