PAM 抗体 (AA 2425-2475)
Quick Overview for PAM 抗体 (AA 2425-2475) (ABIN7452920)
抗原
See all PAM 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 2425-2475
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原理
- Rabbit anti-PAM Antibody, Affinity Purified
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预测反应
- Mouse
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纯化方法
- Affinity Purified
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免疫原
- between AA 2425 and 2475
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亚型
- IgG
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应用备注
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IP: Not recommended.
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- PAM (Peptidylglycine alpha-Amidating Monooxygenase (PAM))
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别名
- PAM
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背景
- Background: In addition to its possible functions as a facilitator of Myc activated transcription, PAM (protein associated with Myc) has also been shown to play a role in mTOR signaling. PAM functions as an E3 ubiquitin ligase for tuberin (TSC2), a negative regulator of the mTOR pathway. Additionally PAM has been shown to function as a guanosine exchange factor (GEF) for Rheb and to facilitate sphingosine-1-phosphate signaling in the mTOR pathway.
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基因ID
- 23077
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NCBI登录号
- NP_055872
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UniProt
- O75592
抗原
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