FKBP4 抗体 (AA 440-459)
Quick Overview for FKBP4 抗体 (AA 440-459) (ABIN7452888)
抗原
See all FKBP4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 440-459
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原理
- Rabbit anti-FKBP4/FKBP52 Antibody, Affinity Purified
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预测反应
- Rabbit
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纯化方法
- Affinity Purified
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免疫原
- between AA 440 and 459
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亚型
- IgG
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应用备注
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IP: Not recommended. Use rabbit anti-FKBP4/FKBP52 antibody A301-427A.
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- FKBP4 (FK506 Binding Protein 4, 59kDa (FKBP4))
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别名
- FKBP4/FKBP52
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背景
- Background: FKBP4/FKBP52 is an immunophilin and target of FK506, a macrolide immunosuppressive drug derived from Streptomyces tsukubaensis. Like other FK506 binding proteins, FKBP52 exhibits peptidyl-prolyl cis-trans isomerase activity, but does not appear to mediate the immunosuppressive activities of FK506. The most studied role of FKBP4/FKBP52 surrounds its involvement in the regulation of steroid receptor signaling. In association with the molecular chaperone Hsp90, FKBP4/FKBP52 is able to influence steroid-hormone binding affinity and transcriptional activity.
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基因ID
- 2288
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NCBI登录号
- NP_002005
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UniProt
- Q02790
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway
抗原
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