CCDC94 抗体 (AA 273-323)
Quick Overview for CCDC94 抗体 (AA 273-323) (ABIN7452810)
抗原
See all CCDC94 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 273-323
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原理
- Rabbit anti-CCDC94 Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 273 and 323
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亚型
- IgG
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应用备注
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IP: 50-100 μL/mg lysate
WB: 1:10,000 - 1:25,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- CCDC94 (Coiled-Coil Domain Containing 94 (CCDC94))
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别名
- CCDC94
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背景
- Background: CCDC94 is part of the spliceosome which catalyzes two sequential transesterification reactions, first the excision of the non-coding intron from pre-mRNA and then the ligation of the coding exons to form the mature mRNA. CCDC94 also plays a role in stabilizing the structure of the spliceosome catalytic core and docking of the branch helix into the active site, producing 5'-exon and lariat intron-3'-intermediates. CCDC94 may protect cells from TP53-dependent apoptosis upon dsDNA break damage through association with PRP19-CD5L complex. [taken from the Universal Protein Resource (UniProt) Q9BW85].
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基因ID
- 55702
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UniProt
- Q9BW85
抗原
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