电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

DKC1 抗体 (AA 390-440)

This anti-DKC1 antibody is a 兔 多克隆 antibody detecting DKC1 in WB 和 IP. Suitable for 人.
产品编号 ABIN7452755
发货至: 中国

Quick Overview for DKC1 抗体 (AA 390-440) (ABIN7452755)

抗原

See all DKC1 抗体
DKC1 (Dyskeratosis Congenita 1, Dyskerin (DKC1))

适用

  • 71
  • 37
  • 29
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1

宿主

  • 73
  • 3
  • 1

克隆类型

  • 67
  • 10
多克隆

标记

  • 40
  • 5
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This DKC1 antibody is un-conjugated

应用范围

  • 57
  • 26
  • 25
  • 23
  • 20
  • 13
  • 13
  • 12
  • 10
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB), Immunoprecipitation (IP)
  • 抗原表位

    • 15
    • 7
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 390-440

    原理

    Rabbit anti-DKC1 Antibody, Affinity Purified

    纯化方法

    Affinity Purified

    免疫原

    between AA 390 and 440

    亚型

    IgG
  • 应用备注

    IP: 5 - 15 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    DKC1 (Dyskeratosis Congenita 1, Dyskerin (DKC1))

    别名

    DKC1

    背景

    Background: Dyskeratosis congenita 1(DKC1) is also known as dyskerin. DKC1 is required for ribosome biogenesis and telomere maintenance. It is a probable catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. DKC1 is also required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme. Defects in DKC1 are a cause of dyskeratosis congenita X-linked recessive (XDKC), a rare progressive bone marrow failure syndrome [taken from the Universal Protein Resource (UniProt) O60832].

    基因ID

    1736

    NCBI登录号

    NP_001354

    UniProt

    O60832

    途径

    Telomere Maintenance
You are here:
Chat with us!