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RAD17 抗体 (AA 564-614)

This anti-RAD17 antibody is a 山羊 多克隆 antibody detecting RAD17 in WB 和 IP. Suitable for 人.
产品编号 ABIN7452689
发货至: 中国

Quick Overview for RAD17 抗体 (AA 564-614) (ABIN7452689)

抗原

See all RAD17 抗体
RAD17

适用

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宿主

  • 96
  • 4
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山羊

克隆类型

  • 99
  • 3
多克隆

标记

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This RAD17 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP)
  • 抗原表位

    • 20
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    AA 564-614

    原理

    Goat anti-Rad17 Antibody, Affinity Purified

    预测反应

    Orangutan

    纯化方法

    Affinity Purified

    免疫原

    between AA 564 and 614

    亚型

    IgG
  • 应用备注

    IP: 40 μL/mg lysate

    WB: 1:2,000 - 1:10,000

    限制

    仅限研究用
  • 浓度

    1000 μg/mL

    缓冲液

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    RAD17

    别名

    Rad17

    背景

    Background: Rad17 is a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein shares strong similarity with DNA replication factor C (RFC), and can form a complex with RFCs. This protein binds to chromatin prior to DNA damage and is phosphorylated by the checkpoint kinase ATR following damage. This protein recruits the RAD1-RAD9-HUS1 checkpoint protein complex onto chromatin after DNA damage, which may be required for its phosphorylation. The phosphorylation of this protein is required for the DNA-damage-induced cell cycle G2 arrest, and is thought to be a critical early event during checkpoint signaling in DNA-damaged cells. [taken from the Universal Protein Resource (UniProt) O75943].

    基因ID

    5884

    NCBI登录号

    NP_579917

    UniProt

    O75943
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