UBR1 抗体 (AA 225-275)
Quick Overview for UBR1 抗体 (AA 225-275) (ABIN7452547)
抗原
See all UBR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 225-275
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原理
- Rabbit anti-UBR1 Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 225 and 275
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亚型
- IgG
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应用备注
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IP: 2 - 5 μg/mg lysate
WB: Not recommended
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- UBR1 (Ubiquitin Protein Ligase E3 Component N-Recognin 1 (UBR1))
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别名
- UBR1
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背景
- Background: UBR1 is an E3 ubiquitin-protein ligase that is a component of the N-end rule pathway. UBR1 recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. UBR1 may be involved in pancreatic homeostasis. UBR1 binds leucine and is a negative regulator of the leucine-mTOR signaling pathway, thereby controlling cell growth [taken from the Universal Protein Resource (UniProt) Q8IWV7].
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基因ID
- 197131
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NCBI登录号
- NP_777576
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UniProt
- Q8IWV7
抗原
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