Mahogunin RING Finger Protein 1 抗体 (AA 505-555)
Quick Overview for Mahogunin RING Finger Protein 1 抗体 (AA 505-555) (ABIN7452524)
抗原
See all Mahogunin RING Finger Protein 1 (MGRN1) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 505-555
-
原理
- Rabbit anti-MGRN1 Antibody, Affinity Purified
-
预测反应
- Gorilla,Chimpanzee
-
纯化方法
- Affinity Purified
-
免疫原
- between AA 505 and 555
-
亚型
- IgG
-
-
anti-Mahogunin, Ring Finger 1 (MGRN1) antibody
MGRN1 适用: 人, 猴 WB, IF, FACS 宿主: 小鼠 Monoclonal 3C3 unconjugated
anti-Mahogunin, Ring Finger 1 (MGRN1) (AA 1-576) antibodyMGRN1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Mahogunin, Ring Finger 1 (MGRN1) (AA 477-576) antibodyMGRN1 适用: 人 WB, IF, ELISA 宿主: 小鼠 Monoclonal 3E1 unconjugated
anti-Mahogunin, Ring Finger 1 (MGRN1) (AA 1-576) antibodyMGRN1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Mahogunin, Ring Finger 1 (MGRN1) (AA 252-301) antibodyMGRN1 适用: 人, 小鼠, 大鼠, 山羊, 豚鼠, 猴, 斑马鱼, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-Mahogunin, Ring Finger 1 (MGRN1) (Middle Region) antibodyMGRN1 适用: 人, 小鼠, 大鼠, 山羊, 豚鼠, 斑马鱼, Cow, 犬, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
IP: 2 - 5 μg/mg lysate
WB: Not recommended
-
限制
- 仅限研究用
-
-
-
浓度
- 1000 μg/mL
-
缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
有效期
- 12 months
-
-
- Mahogunin RING Finger Protein 1 (MGRN1) (Mahogunin, Ring Finger 1 (MGRN1))
-
别名
- MGRN1
-
背景
- Background: MGRN1 (mahogunin RING finger protein 1) is an E3 ubiquitin-protein ligase that mediates monoubiquitination at multiple sites of TSG101 in the presence of UBE2D1, but not of UBE2G1, nor UBE2H. MGRN1 plays a role in the regulation of endosome-to-lysosome trafficking. It impairs MC1R- and MC4R-signaling by competing with GNAS-binding to MCRs and inhibiting agonist-induced cAMP production but does not promote MC1R ubiquitination [taken from the Universal Protein Resource (UniProt) O60291].
-
基因ID
- 23295
-
NCBI登录号
- NP_001135761
-
UniProt
- O60291
-
途径
- Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
-
