SMN1 抗体 (AA 50-100)
Quick Overview for SMN1 抗体 (AA 50-100) (ABIN7452436)
抗原
See all SMN1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 50-100
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原理
- Rabbit anti-SMN1 Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 50 and 100
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亚型
- IgG
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应用备注
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IP: 2 - 5 μg/mg lysate
WB: Not recommended. Use rabbit anti-SMN1 antibody ABIN7452052.
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- SMN1 (Survival of Motor Neuron 1, Telomeric (SMN1))
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别名
- SMN1
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背景
- Background: Survival motor neuron protein (SMN1) has been identified as the gene that is defective in spinal muscular atrophy (SMA), a neurodegenerative autosomal recessive disease characterized by paralysis and muscular atrophy which results from the loss of motor neurons in the spinal cord. There are two closely related SMN genes that do not appear to be functionally redundant. SMN1 represents the telomeric copy while SMN2 represents the centromeric copy. In the cell, SMN1 is part of a large complex of proteins involved in snRNP biogenesis. The functional role of SMN1 is proposed to play a role in messenger and ribosomal RNA transcription and processing.
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基因ID
- 6606
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NCBI登录号
- NP_000335
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UniProt
- Q16637
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途径
- Ribonucleoprotein Complex Subunit Organization
抗原
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