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FKBP5 抗体 (AA 225-275)

The 兔 多克隆 anti-FKBP5 antibody (ABIN7452330) specifically detects FKBP5 in IP. The antibody is reactive with 人 samples.
产品编号 ABIN7452330
发货至: 中国
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Quick Overview for FKBP5 抗体 (AA 225-275) (ABIN7452330)

抗原

See all FKBP5 抗体
FKBP5 (FK506 Binding Protein 5 (FKBP5))

适用

  • 82
  • 43
  • 31
  • 6
  • 6
  • 5
  • 5
  • 4
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1

宿主

  • 72
  • 17
  • 1

克隆类型

  • 55
  • 35
多克隆

标记

  • 37
  • 10
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
  • 1
This FKBP5 antibody is un-conjugated

应用范围

  • 58
  • 28
  • 27
  • 26
  • 15
  • 12
  • 12
  • 11
  • 8
  • 2
  • 1
  • 1
Immunoprecipitation (IP)
  • 抗原表位

    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 225-275

    原理

    Rabbit anti-FKBP5/FKBP51 Antibody, Affinity Purified

    预测反应

    Orangutan

    纯化方法

    Affinity Purified

    免疫原

    between AA 225 and 275

    亚型

    IgG
  • 应用备注

    IP: 2 - 5 μg/mg lysate

    WB: Not recommended. Use rabbit anti-FKBP5/FKBP51 antibody A301-430A.

    限制

    仅限研究用
  • 浓度

    1000 μg/mL

    缓冲液

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    FKBP5 (FK506 Binding Protein 5 (FKBP5))

    别名

    FKBP5/FKBP51

    背景

    Background: FKBP5/FKBP51 is an immunophilin and target of FK506, a macrolide immunosuppressive drug derived from Streptomyces tsukubaensis. Like other FK506 binding proteins, FKBP5/FKBP51 exhibits peptidyl-prolyl cis-trans isomerase activity. The most studied role of FKBP5/FKBP51 surrounds its involvement in the regulation of steroid receptor signaling. In association with the molecular chaperones Hsp90 and Hsp70, FKBP5/FKBP51 is able to influence steroid-hormone binding affinity and transcriptional activity. Recently, FKBP5/FKBP51 has become of interest in the field of psychiatry due to its potential role in cortisol regulation and its relation to mood disorders.

    基因ID

    2289

    NCBI登录号

    NP_004108

    UniProt

    Q13451
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