RNF169 抗体 (AA 200-250)
Quick Overview for RNF169 抗体 (AA 200-250) (ABIN7452249)
抗原
See all RNF169 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 200-250
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原理
- Rabbit anti-RNF169 Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- Between AA 200 and 250
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亚型
- IgG
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anti-Ring Finger Protein 169 (RNF169) antibody
RNF169 适用: 人, 大鼠, 小鼠 WB, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 169 (RNF169) (AA 643-742) antibodyRNF169 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Ring Finger Protein 169 (RNF169) (AA 643-742) antibodyRNF169 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3B6 unconjugated
anti-Ring Finger Protein 169 (RNF169) (AA 215-264) antibodyRNF169 适用: 人, 大鼠, 小鼠, Cow, 犬, 豚鼠, 马, Bat, 小鸡, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 169 (RNF169) (N-Term) antibodyRNF169 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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IP: 2 - 5 μg/mg lysate
WB: Not recommended. ABIN7452249 has not performed satisfactorily when used for WB of RNF169 in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of RNF169.
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- RNF169 (Ring Finger Protein 169 (RNF169))
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别名
- RNF169
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背景
- Background: RING finger protein 169 (RNF169) is a probable E3 ubiquitin-protein ligase that acts as a negative regulator of the repair of double-strand breaks (DSBs) following DNA damage. RNF169 is recruited to DSB repair sites by recognizing and binding ubiquitin catalyzed by RNF168 and competes with TP53BP1 and BRCA1 for association with RNF168-modified chromatin, thereby acting as a negative regulator of DSB repair [taken from the Universal Protein Resource (UniProt) Q8NCN4].
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基因ID
- 254225
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NCBI登录号
- NP_001092108
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UniProt
- Q8NCN4
抗原
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