FZD6 抗体 (AA 656-706)
Quick Overview for FZD6 抗体 (AA 656-706) (ABIN7452245)
抗原
See all FZD6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 656-706
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原理
- Rabbit anti-Frizzled-6 Antibody, Affinity Purified
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预测反应
- Orangutan
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纯化方法
- Affinity Purified
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免疫原
- between AA 656 and 706
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亚型
- IgG
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应用备注
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IP: 2 - 5 μg/mg lysate
WB: Not recommended. ABIN7452245 has not performed satisfactorily when used for WB of Frizzled-6 in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of Frizzled-6.
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- FZD6 (Frizzled Family Receptor 6 (FZD6))
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别名
- Frizzled-6
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背景
- Background: Frizzled-6 is a receptor for Wnt proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin, and activation of wnt target genes. In mice, frizzled-6 is critical to B-cell development.
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基因ID
- 8323
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NCBI登录号
- NP_003497
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UniProt
- O60353
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途径
- WNT signaling, Tube Formation
抗原
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