SPEN 抗体 (AA 3375-3425)
This anti-SPEN antibody is a 兔 多克隆 antibody detecting SPEN in IP. Suitable for 人.
Quick Overview for SPEN 抗体 (AA 3375-3425) (ABIN7452220)
抗原
See all SPEN 抗体
SPEN
(Spen Homolog, Transcriptional Regulator (SPEN))
适用
人
宿主
兔
克隆类型
多克隆
标记
This SPEN antibody is un-conjugated
应用范围
Immunoprecipitation (IP)
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抗原表位
- AA 3375-3425
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原理
- Rabbit anti-SHARP Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 3375 and 3425
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亚型
- IgG
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应用备注
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IP: 2 - 5 μg/mg lysate
WB: Not recommended. ABIN7451040 can be used successfully for WB of enriched preparations (e.g. immunoprecipitated) SHARP.
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- SPEN (Spen Homolog, Transcriptional Regulator (SPEN))
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别名
- SHARP
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背景
- Background: SHARP functions as a transcriptional repressor by interacting with proteins involved in deacetylation such as the NuRD (nucleosome remodeling) complex. SHARP can also repress transcription by interacting with corepressors such as SMRT/NCoR (silencing mediator for retinoid and thyroid receptors/nuclear receptor corepressor). SHARP is able to suppress transcription through the Notch/RBP-J signaling pathway by competing RBP-J binding with the intracellular domain of Notch.
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基因ID
- 23013
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NCBI登录号
- NP_055816
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UniProt
- Q96T58
抗原
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