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SUFUH 抗体 (AA 434-484)

This anti-SUFUH antibody is a 兔 多克隆 antibody detecting SUFUH in WB 和 IP. Suitable for 人 和 小鼠.
产品编号 ABIN7452074
发货至: 中国

Quick Overview for SUFUH 抗体 (AA 434-484) (ABIN7452074)

抗原

See all SUFUH 抗体
SUFUH (Suppressor of Fused Homolog (SUFUH))

适用

  • 50
  • 32
  • 30
  • 7
  • 7
  • 7
  • 7
  • 4
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
人, 小鼠

宿主

  • 47
  • 3

克隆类型

  • 47
  • 3
多克隆

标记

  • 23
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This SUFUH antibody is un-conjugated

应用范围

  • 35
  • 13
  • 13
  • 10
  • 8
  • 6
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Immunoprecipitation (IP)
  • 抗原表位

    • 15
    • 8
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 434-484

    原理

    Rabbit anti-SuFu Antibody, Affinity Purified

    纯化方法

    Affinity Purified

    免疫原

    between AA 434 and 484

    亚型

    IgG
  • 应用备注

    IP: 2 - 5 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    SUFUH (Suppressor of Fused Homolog (SUFUH))

    别名

    SuFu

    背景

    Background: Suppressor of fused (SuFu) is a negative regulator of the hedgehog and beta-catenin signaling pathway. It down-regulates GLI1-mediated transactivation of target genes and is part of a corepressor complex that acts on DNA-bound GLI1. SuFu may also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Additionally, SuFu sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein [taken from the Universal Protein Resource (UniProt) Q9UMX1].

    基因ID

    51684

    NCBI登录号

    NP_057253

    UniProt

    Q9UMX1

    途径

    Hedgehog Signaling, Tube Formation, Maintenance of Protein Location
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