MCM7 抗体 (AA 300-350)
Quick Overview for MCM7 抗体 (AA 300-350) (ABIN7451867)
抗原
See all MCM7 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 300-350
-
原理
- Rabbit anti-MCM7 Antibody, Affinity Purified
-
纯化方法
- Affinity Purified
-
免疫原
- between AA 300 and 350
-
亚型
- IgG
-
-
-
-
应用备注
-
IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
-
限制
- 仅限研究用
-
-
-
浓度
- 200 μg/mL
-
缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
有效期
- 12 months
-
-
- MCM7 (Minichromosome Maintenance Complex Component 7 (MCM7))
-
别名
- MCM7
-
背景
- Background: The MCM (Mini-Chromosome Maintenance) complex is a key component of the pre-replication complex involved in replication licensing which restricts DNA replication to only once per cell cycle. The MCM complex is a heterohexamer of MCM2, MCM3, MCM4, MCM5, MCM6, and MCM7. MCM7 is part of the core MCM complex that includes MCM4, MCM6, and MCM7. The core complex possesses DNA helicase activity. MCM7 has been shown to interact with CDK4 and p27Kip1 to regulate cell cycle progression. MCM7 has also been shown to interact with ATR-interacting protein (ATRIP)-ATR to function as a transmitter of DNA damage signals from replication forks to S-phase checkpoint machinery.
-
基因ID
- 4176
-
NCBI登录号
- NP_005907
-
UniProt
- P33993
-
途径
- DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
抗原
-