DFFA 抗体 (C-Term)
Quick Overview for DFFA 抗体 (C-Term) (ABIN7451735)
抗原
See all DFFA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Rabbit anti-DFF35/DFFA Antibody, Affinity Purified
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预测反应
- Monkey
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纯化方法
- Affinity Purified
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免疫原
- C-terminus
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亚型
- IgG
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应用备注
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IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- DFFA (DNA Fragmentation Factor, 45kDa, alpha Polypeptide (DFFA))
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别名
- DFF35/DFFA
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背景
- Background: DFF (DNA fragmentation factor) is the principle endonuclease responsible for DNA cleavage during apoptosis and exists as a heterodimer formed between the inhibitory subunit, DFF45, and the DNA nuclease, DFF40. DFF35/DFFA is a 35 kDa splice variant of the inhibitory subunit, DFF45. Similar to DFF45, DFF35 has been shown to heterodimerize with DFF40 and also negatively regulate its nuclease activity. In addition to regulating DFF40 activity, DFF35 has also been found to assist in the synthesis and folding of the DFF40 endonuclease.
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基因ID
- 1676
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NCBI登录号
- NP_998731
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UniProt
- O00273
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途径
- Apoptosis, Caspase Cascade in Apoptosis
抗原
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