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BRAP 抗体 (AA 560-592)

BRAP 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7451664
发货至: 中国
  • 抗原 See all BRAP 抗体
    BRAP (BRCA1 Associated Protein (BRAP))
    抗原表位
    • 14
    • 7
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 560-592
    适用
    • 29
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 28
    • 1
    克隆类型
    • 28
    • 1
    多克隆
    标记
    • 15
    • 4
    • 3
    • 3
    • 2
    • 2
    This BRAP antibody is un-conjugated
    应用范围
    • 22
    • 20
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP)
    原理
    Rabbit anti-BRAP Antibody, Affinity Purified
    纯化方法
    Affinity Purified
    免疫原
    between AA 560 and 592
    亚型
    IgG
    Top Product
    Discover our top product BRAP Primary Antibody
  • 应用备注

    IP: 2 - 5 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    限制
    仅限研究用
  • 浓度
    1000 μg/mL
    缓冲液
    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    有效期
    12 months
  • 抗原
    BRAP (BRCA1 Associated Protein (BRAP))
    别名
    BRAP (BRAP 产品)
    别名
    imp antibody, MGC68778 antibody, zgc:92894 antibody, BRAP antibody, BRAP2 antibody, IMP antibody, RNF52 antibody, 3010002G07Rik antibody, BRCA1 associated protein S homeolog antibody, BRCA1 associated protein antibody, BRCA1-associated protein antibody, brca1-associated protein antibody, brap.S antibody, brap antibody, BRAP antibody, NAEGRDRAFT_81654 antibody, CC1G_00971 antibody, CpipJ_CPIJ003557 antibody, Tsp_05101 antibody, LOC100282389 antibody, Brap antibody
    背景
    Background: BRCA1-associated protein (BRAP) negatively regulates MAP kinase activation by limiting the formation of Raf/MEK complexes probably by inactivation of the KSR1 scaffold protein. BRAP acts as a Ras responsive E3 ubiquitin ligase that, on activation of Ras, is modified by auto-polyubiquitination resulting in the release of inhibition of Raf/MEK complex formation. BRAP may also act as a cytoplasmic retention protein with a role in regulating nuclear transport [taken from the Universal Protein Resource (UniProt) Q7Z569].
    基因ID
    8315
    NCBI登录号
    NP_006759
    UniProt
    Q7Z569
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