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BRAP 抗体 (AA 560-592)

The 兔 多克隆 anti-BRAP antibody (ABIN7451664) specifically detects BRAP in WB 和 IP. The antibody is reactive with 人 samples.
产品编号 ABIN7451664
发货至: 中国
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中国
北京 101111
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Room 801-803
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Quick Overview for BRAP 抗体 (AA 560-592) (ABIN7451664)

抗原

See all BRAP 抗体
BRAP (BRCA1 Associated Protein (BRAP))

适用

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宿主

  • 23
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克隆类型

  • 23
  • 2
多克隆

标记

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This BRAP antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP)
  • 抗原表位

    • 9
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    AA 560-592

    原理

    Rabbit anti-BRAP Antibody, Affinity Purified

    纯化方法

    Affinity Purified

    免疫原

    between AA 560 and 592

    亚型

    IgG
  • 应用备注

    IP: 2 - 5 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    限制

    仅限研究用
  • 浓度

    1000 μg/mL

    缓冲液

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    BRAP (BRCA1 Associated Protein (BRAP))

    别名

    BRAP

    背景

    Background: BRCA1-associated protein (BRAP) negatively regulates MAP kinase activation by limiting the formation of Raf/MEK complexes probably by inactivation of the KSR1 scaffold protein. BRAP acts as a Ras responsive E3 ubiquitin ligase that, on activation of Ras, is modified by auto-polyubiquitination resulting in the release of inhibition of Raf/MEK complex formation. BRAP may also act as a cytoplasmic retention protein with a role in regulating nuclear transport [taken from the Universal Protein Resource (UniProt) Q7Z569].

    基因ID

    8315

    NCBI登录号

    NP_006759

    UniProt

    Q7Z569
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