CHD7 抗体 (AA 2025-2075)
Quick Overview for CHD7 抗体 (AA 2025-2075) (ABIN7451215)
抗原
See all CHD7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 2025-2075
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原理
- Rabbit anti-CHD7 Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 2025 and 2075
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亚型
- IgG
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应用备注
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IP: 2 - 10 μg/mg lysate
WB: Not recommended. Use rabbit anti-CHD7 antibody ABIN7453314.
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- CHD7 (Chromodomain Helicase DNA Binding Protein 7 (CHD7))
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别名
- CHD7
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背景
- Background: CHD7 is a member of the CHD (chromodomain-helicase-DNA-binding) family of proteins that interacts with nucleosomes and plays a role in chromatin remodeling to modulate transcription. The members of the CHD family of proteins possess 3 common structural and functional domains: a chromodomain (chromatin organization modifier), an SNF2-like helicase/ATPase domain, and a C-terminal DNA-binding domain. CHD7 is implicated to play a role in development. Mutations in CHD7 are associated with CHARGE syndrome, a multi-symptom syndrome characterized by congenital anomalies and malformations of the heart, inner ear, retina, and palate.
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基因ID
- 55636
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NCBI登录号
- NP_060250
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UniProt
- Q9P2D1
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途径
- Sensory Perception of Sound, Chromatin Binding
抗原
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