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Neurofibromin 1 抗体 (AA 1-50)

This anti-Neurofibromin 1 antibody is a 兔 多克隆 antibody detecting Neurofibromin 1 in IP. Suitable for 人.
产品编号 ABIN7451097
发货至: 中国

Quick Overview for Neurofibromin 1 抗体 (AA 1-50) (ABIN7451097)

抗原

See all Neurofibromin 1 (NF1) 抗体
Neurofibromin 1 (NF1)

适用

  • 64
  • 51
  • 35
  • 2
  • 2
  • 2
  • 2
  • 1

宿主

  • 72
  • 8

克隆类型

  • 72
  • 8
多克隆

标记

  • 28
  • 5
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Neurofibromin 1 antibody is un-conjugated

应用范围

  • 39
  • 39
  • 27
  • 21
  • 14
  • 13
  • 10
  • 9
  • 6
  • 5
  • 3
  • 1
  • 1
Immunoprecipitation (IP)
  • 抗原表位

    • 15
    • 15
    • 15
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 1-50

    原理

    Rabbit anti-NF1 Antibody, Affinity Purified

    预测反应

    Mouse,Rat

    纯化方法

    Affinity Purified

    免疫原

    Between AA 1 and 50

    亚型

    IgG
  • 应用备注

    IP: 2 - 10 μg/mg lysate

    WB: Not recommended. ABIN7451097 has not performed satisfactorily when used for WB of NF1 in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of NF1.

    限制

    仅限研究用
  • 浓度

    1000 μg/mL

    缓冲液

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    Neurofibromin 1 (NF1)

    别名

    NF1

    背景

    Background: Inactivating mutations in NF1 (neurofibromin 1) result in neurofibromatosis type I (NF1) which is characterized by Schwann cell neurofibromas, café-au-lait spots, and benign lesions of the iris. At the cellular level, NF1 functions as a negative regulator of Ras activity. Loss of NF1 leads to increased levels of active Ras-GTP which is important for the formation and maintenance of Schwann cell tumors.

    基因ID

    4763

    NCBI登录号

    NP_001035957

    UniProt

    P21359

    途径

    cAMP Metabolic Process, Regulation of long-term Neuronal Synaptic Plasticity
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