MDC1 抗体 (AA 900-950)
Quick Overview for MDC1 抗体 (AA 900-950) (ABIN7451086)
抗原
See all MDC1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 900-950
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原理
- Rabbit anti-Mdc1/Nfbd1 Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- Between AA 900 and 950
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亚型
- IgG
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anti-Mdc1 (MDC1) (AA 1-100) antibody
MDC1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mdc1 (MDC1) antibodyMDC1 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Mdc1 (MDC1) (AA 31-130) antibodyMDC1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Mdc1 (MDC1) (AA 1-350) antibodyMDC1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mdc1 (MDC1) (N-Term) antibodyMDC1 适用: 小鼠 WB, IF, ICC 宿主: 小鼠 Monoclonal P2B11 unconjugated
anti-Mdc1 (MDC1) (N-Term) antibody (HRP)MDC1 适用: 小鼠 WB, IF, ICC 宿主: 小鼠 Monoclonal P2B11 HRP
anti-Mdc1 (MDC1) (N-Term) antibody (FITC)MDC1 适用: 小鼠 WB, IF, ICC 宿主: 小鼠 Monoclonal P2B11 FITC
anti-Mdc1 (MDC1) (N-Term) antibody (Biotin)MDC1 适用: 小鼠 WB, IF, ICC 宿主: 小鼠 Monoclonal P2B11 Biotin
anti-Mdc1 (MDC1) (N-Term) antibody (PE)MDC1 适用: 小鼠 WB, IF, ICC 宿主: 小鼠 Monoclonal P2B11 PE
anti-Mdc1 (MDC1) (N-Term) antibody (APC)MDC1 适用: 小鼠 WB, IF, ICC 宿主: 小鼠 Monoclonal P2B11 APC
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应用备注
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IP: 2 - 10 μg/mg lysate
WB: Not recommended. ABIN7451086 has not performed satisfactorily when used for WB of Mdc1/Nfbd1 in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of Mdc1/Nfbd1.
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- MDC1 (Mdc1 (MDC1))
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别名
- Mdc1/Nfbd1
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背景
- Background: Mediator of DNA damage checkpoint protein 1 (Mdc1) is required for checkpoint mediated cell cycle arrest in response to DNA damage within both the S phase and G2/M phases of the cell cycle. It may serve as a scaffold for the recruitment of DNA repair and signal transduction proteins to discrete foci of DNA damage marked by 'Ser-139' phosphorylation of histone H2AFX. It is also required for downstream events subsequent to the recruitment of these proteins. These include phosphorylation and activation of the ATM, CHEK1 and CHEK2 kinases, and stabilization of TP53 and apoptosis [taken from the Universal Protein Resource (UniProt) Q5PSV9].
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基因ID
- 240087
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NCBI登录号
- NP_001010833
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UniProt
- Q5PSV9
抗原
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