NSMCE2 抗体 (AA 197-247)
Quick Overview for NSMCE2 抗体 (AA 197-247) (ABIN7451060)
抗原
See all NSMCE2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 197-247
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原理
- Rabbit anti-MMS21 Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- Between AA 197 and 247
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亚型
- IgG
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应用备注
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IP: 2 - 10 μg/mg lysate
WB: Not recommended. ABIN7451060 has not performed satisfactorily when used for WB of MMS21 in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of MMS21.
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- NSMCE2 (E3 SUMO-Protein Ligase NSE2 (NSMCE2))
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别名
- MMS21
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背景
- Background: The human MMS21 (Methyl Methanesulfonate-Sensitivity protein 21) homolog is also known as E3 SUMO-protein ligase NSE2. MMS21 is an E3 SUMO-protein ligase component of the SMC5-SMC6 complex, a complex involved in DNA double-strand break repair by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks [taken from the Universal Protein Resource (UniProt) Q96MF7].
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基因ID
- 286053
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NCBI登录号
- NP_775956
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UniProt
- Q96MF7
抗原
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