Importin 9 抗体 (AA 991-1041)
Quick Overview for Importin 9 抗体 (AA 991-1041) (ABIN7450998)
抗原
See all Importin 9 (IPO9) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 991-1041
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原理
- Rabbit anti-IPO9 Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- Between AA 991 and 1041
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亚型
- IgG
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anti-Importin 9 (IPO9) (AA 158-176) antibody
IPO9 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Importin 9 (IPO9) (AA 1-388) antibodyIPO9 适用: 人 WB, IHC (p) 宿主: 小鼠 Monoclonal 1815CT202-22-8-37 unconjugated
anti-Importin 9 (IPO9) (C-Term) antibodyVerified IPO9 适用: 人 ELISA, IHC, ICC 宿主: 山羊 Polyclonal unconjugated
anti-Importin 9 (IPO9) (C-Term) antibodyIPO9 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Importin 9 (IPO9) (AA 79-106), (N-Term) antibodyIPO9 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB26877 unconjugated
anti-Importin 9 (IPO9) (AA 339-367) antibodyIPO9 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB19813 unconjugated
anti-Importin 9 (IPO9) (C-Term) antibodyIPO9 适用: 人 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Importin 9 (IPO9) (AA 850-950) antibodyIPO9 适用: 人, 小鼠, 大鼠, 犬, Cow, 小鸡, 猴, Opossum WB 宿主: 兔 Polyclonal unconjugated
anti-Importin 9 (IPO9) (AA 827-1041) antibodyIPO9 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Importin 9 (IPO9) (AA 480-605) antibodyIPO9 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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IP: 2 - 10 μg/mg lysate
WB: 1:500 - 1:2,500
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- Importin 9 (IPO9)
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别名
- IPO9
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背景
- Background: Importin-9 (IPO9) functions in nuclear protein import as a nuclear transport receptor. IPO9 serves as receptor for nuclear localization signals (NLS) in cargo substrates. It is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity). IPO9 mediates the nuclear import of H2B histone (By similarity), RPS7 and RPL18A. It prevents the cytoplasmic aggregation of RPS7 and RPL18A by shielding exposed basic domains. IPO9 may also import H2A, H3, H4 histones (By similarity), RPL4 and RPL6 [taken from the Universal Protein Resource (UniProt) Q96P70].
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基因ID
- 55705
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UniProt
- Q96P70
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途径
- Protein targeting to Nucleus
抗原
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