UBQLN4 抗体 (AA 1-50)
Quick Overview for UBQLN4 抗体 (AA 1-50) (ABIN7450868)
抗原
See all UBQLN4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-50
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原理
- Rabbit anti-UBQLN4/CIP75/Ubiquilin 4 Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- Between AA 1 and 50
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亚型
- IgG
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anti-Ubiquilin 4 (UBQLN4) (AA 300-390) antibody
UBQLN4 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ubiquilin 4 (UBQLN4) (AA 287-336) antibodyUBQLN4 适用: 人, 小鼠, 大鼠, Cow, 马, 兔, 犬, Pig, 猴, 小鸡, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquilin 4 (UBQLN4) (Middle Region) antibodyUBQLN4 适用: 人, 小鼠, 大鼠, Cow, 马, 兔, 豚鼠, 斑马鱼, 犬, Pig, 绵羊 WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquilin 4 (UBQLN4) (AA 201-250) antibodyUBQLN4 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ubiquilin 4 (UBQLN4) (N-Term) antibodyUBQLN4 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- UBQLN4 (Ubiquilin 4 (UBQLN4))
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别名
- UBQLN4/CIP75/Ubiquilin 4
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背景
- Background: Ubiquilin-4 (UBQLN4) plays a role in the regulation of protein degradation via the ubiquitin-proteasome system (UPS). It mediates the proteasomal targeting of misfolded or accumulated proteins for degradation by binding (via UBA domain) to their polyubiquitin chains and by interacting (via ubiquitin-like domain) with the subunits of the proteasome. UBQLN4 Plays a role in the regulation of the proteasomal degradation of non-ubiquitinated GJA1 (By similarity). It acts as an adapter protein that recruits UBQLN1 to the autophagy machinery and mediates the association of UBQLN1 with autophagosomes and the autophagy-related protein LC3 (MAP1LC3A/B/C) and may assist in the maturation of autophagosomes to autolysosomes by mediating autophagosome-lysosome fusion (PubMed:23459205) [taken from NCBI Entrez Gene (Gene ID: 56893)].
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基因ID
- 56893
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UniProt
- Q9NRR5
抗原
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