TFEB 抗体 (AA 426-476)
Quick Overview for TFEB 抗体 (AA 426-476) (ABIN7450814)
抗原
See all TFEB 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 426-476
-
原理
- Rabbit anti-TFEB Antibody, Affinity Purified
-
纯化方法
- Affinity Purified
-
免疫原
- Between AA 426 and 476
-
亚型
- IgG
-
-
anti-Transcription Factor EB (TFEB) (AA 1-476) antibody
TFEB 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal S1 unconjugated
anti-Transcription Factor EB (TFEB) (Middle Region) antibodyTFEB 适用: 人, Cow, 犬, 马, 山羊, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor EB (TFEB) (AA 1-476) antibodyTFEB 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor EB (TFEB) (AA 1-220) antibodyTFEB 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor EB (TFEB) (N-Term) antibodyTFEB 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor EB (TFEB) (N-Term) antibodyTFEB 适用: 人 WB, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor EB (TFEB) (AA 1-476) antibodyTFEB 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Transcription Factor EB (TFEB) (Internal Region) antibodyVerified TFEB 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Transcription Factor EB (TFEB) antibodyTFEB 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal unconjugated
-
-
应用备注
-
IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
-
限制
- 仅限研究用
-
-
-
浓度
- 1000 μg/mL
-
缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
有效期
- 12 months
-
-
- TFEB (Transcription Factor EB (TFEB))
-
别名
- TFEB
-
背景
- Background: Transcription factor EB (TFEB) specifically recognizes and binds E-box sequences (3'-CANNTG-5'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFE3 or MITF. In association with TFE3, TFEB activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4+ T-cells and thymus-dependent humoral immunity. TFEB specifically recognizes and binds the CLEAR-box sequence (5'-GTCACGTGAC-3') present in the regulatory region of many lysosomal genes, leading to activate their expression, thus, TFEB plays a central role in expression of lysosomal genes. TFEB also specifically recognizes the gamma-E3 box, a subset of E-boxes, present in the heavy-chain immunoglobulin enhancer [taken from the Universal Protein Resource (UniProt) P19484].
-
基因ID
- 7942
-
NCBI登录号
- NP_009093
-
UniProt
- P19484
抗原
-
