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Stim2 抗体 (AA 600-650)

This 兔 多克隆 anti-Stim2 antibody specifically detects Stim2 in WB 和 IP. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN7450784
发货至: 中国
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Quick Overview for Stim2 抗体 (AA 600-650) (ABIN7450784)

抗原

See all Stim2 抗体
Stim2 (Stromal Interaction Molecule 2 (Stim2))

适用

  • 34
  • 12
  • 9
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 31
  • 2
  • 1

克隆类型

  • 34
多克隆

标记

  • 23
  • 4
  • 3
  • 2
  • 1
  • 1
This Stim2 antibody is un-conjugated

应用范围

  • 30
  • 24
  • 16
  • 6
  • 5
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), Immunoprecipitation (IP)
  • 抗原表位

    • 8
    • 6
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 600-650

    原理

    Rabbit anti-STIM2 Antibody, Affinity Purified

    纯化方法

    Affinity Purified

    免疫原

    Between AA 600 and 650

    亚型

    IgG
  • 应用备注

    IP: 2 - 10 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    限制

    仅限研究用
  • 浓度

    1000 μg/mL

    缓冲液

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    Stim2 (Stromal Interaction Molecule 2 (Stim2))

    别名

    STIM2

    背景

    Background: STIM2 (stromal interaction molecule 2) plays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores. Stim2 functions as a highly sensitive Ca(2+) sensor in the endoplasmic reticulum which activates both store-operated and store-independent Ca(2+)-influx. It regulates basal cytosolic and endoplasmic reticulum Ca(2+) concentrations. Upon mild variations of the endoplasmic reticulum Ca(2+) concentration, STIM2 translocates from the endoplasmic reticulum to the plasma membrane where it probably activates the Ca(2+) release-activated Ca(2+) (CRAC) channels ORAI1, ORAI2 and ORAI. STIM2 may inhibit STIM1-mediated Ca(2+) influx  [taken from the Universal Protein Resource (UniProt) Q9P246].

    基因ID

    57620

    NCBI登录号

    NP_065911

    UniProt

    Q9P246

    途径

    TCR Signaling, BCR Signaling
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