Stim2 抗体 (C-Term, Intracellular)
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Quick Overview for Stim2 抗体 (C-Term, Intracellular) (ABIN7043782)
抗原
See all Stim2 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 583-597, C-Term, Intracellular
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原理
- A Rabbit Polyclonal Antibody to STIM2
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Rat,mouse,bovine - identical
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产品特性
- Anti-STIM2 Antibody (ABIN7043782, ABIN7044028 and ABIN7044029) is a highly specific antibody directed against an epitope of the mouse protein. The antibody can be used in western blot, immunocytochemistry, and immunohistochemistry applications. It has been designed to recognize STIM2 from human, rat, and mouse samples.
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
- SAEKQWEVPDTASEC, corresponding to amino acid residues 583-597 of human STIM2
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亚型
- IgG
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anti-Stromal Interaction Molecule 2 (Stim2) (AA 60-180) antibody
Stim2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Stromal Interaction Molecule 2 (Stim2) (AA 471-656) antibodyStim2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Stromal Interaction Molecule 2 (Stim2) (N-Term) antibodyStim2 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 绵羊 Polyclonal unconjugated
anti-Stromal Interaction Molecule 2 (Stim2) (AA 98-127), (N-Term) antibodyStim2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB19223 unconjugated
anti-Stromal Interaction Molecule 2 (Stim2) (AA 98-127) antibodyStim2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Stromal Interaction Molecule 2 (Stim2) (AA 663-712) antibodyStim2 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Stromal Interaction Molecule 2 (Stim2) (AA 600-650) antibodyStim2 适用: 人, 小鼠 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Stromal Interaction Molecule 2 (Stim2) (AA 650-700) antibodyStim2 适用: 人, 小鼠 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Stromal Interaction Molecule 2 (Stim2) (AA 97-127), (N-Term) antibodyStim2 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Stromal Interaction Molecule 2 (Stim2) (C-Term) antibodyStim2 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB: 1:200
FC: The optimal concentration should be determined by the user
ICC: 1:100
IHC: 1:100
IP: The optimal concentration should be determined by the user
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说明
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Cited Application: IP|ICC
Negative Control: (ABIN7237296)
Blocking Peptide: (ABIN7237296)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 25 μL, 50 μL or 0.2 mL double distilled water (DDW), depending on the sample size.
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浓度
- 0.8 mg/mL
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缓冲液
- PBS pH 7.4, 1 % BSA with 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C
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- Stim2 (Stromal Interaction Molecule 2 (Stim2))
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别名
- STIM2
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背景
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Synonyms: Stromal interaction molecule 2
Description: Cytosolic Ca2+ has long been known to act as a key second messenger in many intracellular pathways including synaptic transmission, muscle contraction, hormonal secretion, cell growth and proliferation.1,2 The mechanism controlling the influx of intracellular Ca2+ either by calcium-release-activated Ca2+ channels (CRAC) or from intracellular stores has lately become the focus of intense research.Recently, several key players of the store-operated complex have been identified: the Orai family consists of three members: Orai1-3, and the STIM family, which consists of two members, STIM1 and STIM2.3 Orai1 (also known as CRACM1) acts as the store-operated calcium channel (SOC) and STIM1 as the endoplasmic reticulum (ER) Ca2+ sensor.3,4While STIM1 appears to be localized intracellularly at the ER membrane and at a much lower extent on the cell surface of several cell types, STIM2 appears to be localized solely at the ER membrane.5 The function of STIM2 still remains elusive and several models have been suggested.6-8
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基因ID
- 57620
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NCBI登录号
- NM_020860
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UniProt
- Q9P246
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途径
- TCR Signaling, BCR Signaling
抗原
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