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SBDS 抗体 (AA 175-225)

This anti-SBDS antibody is a 兔 多克隆 antibody detecting SBDS in WB 和 IP. Suitable for 人.
产品编号 ABIN7450730
发货至: 中国

Quick Overview for SBDS 抗体 (AA 175-225) (ABIN7450730)

抗原

See all SBDS 抗体
SBDS (Shwachman-Bodian-Diamond Syndrome (SBDS))

适用

  • 35
  • 16
  • 16
  • 7
  • 4
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2

宿主

  • 33
  • 2

克隆类型

  • 30
  • 5
多克隆

标记

  • 18
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
This SBDS antibody is un-conjugated

应用范围

  • 17
  • 10
  • 8
  • 6
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunoprecipitation (IP)
  • 抗原表位

    • 5
    • 3
    • 3
    • 3
    • 1
    • 1
    AA 175-225

    原理

    Rabbit anti-Shwachman-Bodian-Diamond Syndrome/SBDS Antibody, Affinity Purified

    预测反应

    Bovine,Orangutan

    纯化方法

    Affinity Purified

    免疫原

    Between AA 175 and 225

    亚型

    IgG
  • 应用备注

    IP: 2 - 10 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    限制

    仅限研究用
  • 浓度

    1000 μg/mL

    缓冲液

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    SBDS (Shwachman-Bodian-Diamond Syndrome (SBDS))

    别名

    Shwachman-Bodian-Diamond Syndrome/SBDS

    背景

    Background: Shwachman-Bodian-Diamond Syndrome/SBDS is required for the assembly of mature ribosomes and ribosome biogenesis. Together with EFTUD1, it triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. SBDS is required for normal levels of protein synthesis. It may play a role in cellular stress resistance and cellular response to DNA damage. It may also play a role in cell proliferation [taken from the Universal Protein Resource (UniProt) Q9Y3A5].

    基因ID

    51119

    UniProt

    Q9Y3A5

    途径

    Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
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