PTK2B 抗体 (AA 959-1009)
Quick Overview for PTK2B 抗体 (AA 959-1009) (ABIN7450623)
抗原
See all PTK2B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 959-1009
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原理
- Rabbit anti-PYK2 Antibody, Affinity Purified
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预测反应
- Mouse,Rat
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纯化方法
- Affinity Purified
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免疫原
- Between AA 959 and 1009
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亚型
- IgG
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应用备注
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- PTK2B (PTK2B Protein tyrosine Kinase 2 beta (PTK2B))
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别名
- PYK2
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背景
- Background: Protein tyrosine kinase 2 (PYK2) is a non-receptor protein-tyrosine kinase that regulates reorganization of the actin cytoskeleton, cell polarization, cell migration, adhesion, spreading and bone remodeling. PYK2 plays a role in the regulation of the humoral immune response, and is required for normal levels of marginal B-cells in the spleen and normal migration of splenic B-cells. It is required for normal macrophage polarization and migration towards sites of inflammation [taken from the Universal Protein Resource (UniProt) Q14289].
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基因ID
- 2185
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NCBI登录号
- NP_775266
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UniProt
- Q14289
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途径
- EGFR Signaling Pathway, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Cellular Glucan Metabolic Process, Cell-Cell Junction Organization, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Protein targeting to Nucleus, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, Positive Regulation of fat Cell Differentiation, VEGF Signaling
抗原
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