PHLPP2 抗体 (C-Term)
Quick Overview for PHLPP2 抗体 (C-Term) (ABIN7450565)
抗原
See all PHLPP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Rabbit anti-PHLPPL Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 1275 and C-term
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亚型
- IgG
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anti-PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2) (C-Term) antibody
PHLPP2 适用: 人, 小鼠 WB, ELISA, IHC, IHC (p), IP 宿主: 兔 Polyclonal unconjugated
anti-PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2) (AA 1295-1323), (C-Term) antibodyPHLPP2 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB15007 unconjugated
anti-PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2) (C-Term) antibodyVerified PHLPP2 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
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应用备注
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- PHLPP2 (PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2))
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别名
- PHLPPL
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背景
- Background: PHLPPL (PH domain leucine-rich repeat-containing protein phosphatase-like) is responsible for the dephosphorylation and subsequent inactivation of Akt. Akt is a signaling protein critical to the balance of cell survival and apoptosis. Dephosphorylation of Akt by PHLPPL has been demonstrated to trigger apoptosis and suppress tumor cell growth. PHLPPL is also known as PHLPPL2 and functions similarly to its relative, PHLPP1. Recent studies show that PHLPPL and PHLPP selectively terminate Akt-signaling by targeting specific Akt isoforms.
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基因ID
- 23035
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NCBI登录号
- NP_055835
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UniProt
- Q6ZVD8
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途径
- PI3K-Akt Signaling, Fc-epsilon Receptor Signaling Pathway
抗原
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