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LIN28B 抗体 (AA 1-50)

This 兔 多克隆 anti-LIN28B antibody specifically detects LIN28B in WB 和 IP. The antibody is reactive with 人 samples.
产品编号 ABIN7450415
发货至: 中国
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北京 101111
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Room 801-803
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Quick Overview for LIN28B 抗体 (AA 1-50) (ABIN7450415)

抗原

See all LIN28B 抗体
LIN28B (Lin-28 Homolog B (LIN28B))

适用

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宿主

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克隆类型

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多克隆

标记

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This LIN28B antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP)
  • 抗原表位

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    AA 1-50

    原理

    Rabbit anti-LIN28B Antibody, Affinity Purified

    纯化方法

    Affinity Purified

    免疫原

    Between AA 1 and 50

    亚型

    IgG
  • 应用备注

    IP: 2 - 10 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    LIN28B (Lin-28 Homolog B (LIN28B))

    别名

    LIN28B

    背景

    Background: Lin-28 homolog B (LIN28B) acts as a suppressor of microRNA (miRNA) biogenesis by specifically binding the precursor let-7 (pre-let-7), a miRNA precursor. LIN28B acts by binding pre-let-7 and recruiting ZCCHC11/TUT4 uridylyltransferase, leading to the terminal uridylation of pre-let-7. LIN28B specifically recognizes the 5'-GGAG-3' motif in the terminal loop of pre-let-7. It also recognizes and binds non pre-let-7 pre-miRNAs that contain the 5'-GGAG-3' motif in the terminal loop, leading to their terminal uridylation and subsequent degradation [taken from the Universal Protein Resource (UniProt) Q6ZN17].

    基因ID

    389421

    NCBI登录号

    NP_001004317

    UniProt

    Q6ZN17
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