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LIN28B 抗体 (AA 95-128)

LIN28B 适用: 人 WB, FACS, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5536364
发货至: 中国
  • 抗原 See all LIN28B 抗体
    LIN28B (Lin-28 Homolog B (LIN28B))
    抗原表位
    • 11
    • 8
    • 7
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 95-128
    适用
    • 55
    • 10
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 54
    • 1
    • 1
    克隆类型
    • 53
    • 3
    多克隆
    标记
    • 35
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LIN28B antibody is un-conjugated
    应用范围
    • 41
    • 27
    • 25
    • 23
    • 21
    • 6
    • 6
    • 4
    • 4
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This LIN28B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 95-128 amino acids from the Central region of human LIN28B.
    亚型
    Ig Fraction
    Top Product
    Discover our top product LIN28B Primary Antibody
  • 应用备注
    For IHC-P starting dilution is: 1:25

    For WB starting dilution is: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.33 mg/mL
    缓冲液
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    LIN28B (Lin-28 Homolog B (LIN28B))
    别名
    LIN28B (LIN28B 产品)
    别名
    csdd2 antibody, LIN-28 antibody, CSDD2 antibody, 2810403D23Rik antibody, D030047M17Rik antibody, Lin-28.2 antibody, lin-28 homolog B antibody, lin-28 homolog B S homeolog antibody, lin-28 homolog B (C. elegans) antibody, LIN28B antibody, lin28b antibody, lin28b.S antibody, Lin28b antibody
    背景
    Lin-28 homolog B (LIN28B) is overexpressed in hepatocellular carcinoma. The heterochronic gene lin-28 is a key regulator of developmental timing in the nematode Caenorhabditis elegans. Similar with lin-28 proteins, LIN28B conserves a cold shock domain and a pair of CCHC zinc finger domains. Phylogenetic analysis suggests that they might arise as a result of duplication from an ancestral gene. Overexpression of LIN28B was noted in most HCC cell lines and clinical samples. A short LIN28B isoform was also identified in non-tumor liver tissue and fetal liver. Although predominantly localized in the cytoplasm, LIN28B protein shows cell cycle-dependent nuclear translocation in Huh7 cells. Induced expression of exogenous LIN28B in a tet-off cell line promoted cancer cell proliferation.
    分子量
    27 kDa
    基因ID
    389421
    UniProt
    Q6ZN17
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