ZBTB33 抗体 (AA 375-425)
Quick Overview for ZBTB33 抗体 (AA 375-425) (ABIN7450383)
抗原
See all ZBTB33 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 375-425
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原理
- Rabbit anti-Kaiso Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 375 and 425
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亚型
- IgG
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应用备注
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- ZBTB33 (Zinc Finger and BTB Domain Containing 33 (ZBTB33))
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别名
- Kaiso
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背景
- Background: Transcriptional regulator Kaiso possesses bimodal DNA-binding specificity and binds to methylated CGCG and also to the non-methylated consensus KAISO-binding site TCCTGCNA. Kaiso contains an N-terminal POZ/BTB domain and 3 C-terminal zinc finger motifs. It recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters. Kaiso may contribute to the repression of target genes of the Wnt signaling pathway, and may also activate transcription of a subset of target genes by the recruitment of catenin delta-2 (CTNND2). Its interaction with catenin delta-1 (CTNND1) inhibits binding to both methylated and non-methylated DNA. [taken from NCBI Entrez Gene (Gene ID: 10009)].
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基因ID
- 10009
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NCBI登录号
- NP_006768
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UniProt
- Q86T24
抗原
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