FMR1 抗体 (AA 582-632)
Quick Overview for FMR1 抗体 (AA 582-632) (ABIN7450257)
抗原
See all FMR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 582-632
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原理
- Rabbit anti-FMR1/FMRP Antibody, Affinity Purified
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预测反应
- Orangutan
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纯化方法
- Affinity Purified
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免疫原
- Between AA 582 and 632
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亚型
- IgG
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应用备注
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- FMR1 (Fragile X Mental Retardation 1 (FMR1))
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别名
- FMR1/FMRP
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背景
- Background: Fragile X mental retardation protein 1 is the product of the gene FMR1, also known as FMRP. This protein binds RNA and is associated with polysomes. FMRP may also be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1).
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基因ID
- 2332
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UniProt
- Q06787, Q86787
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途径
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
抗原
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