FAT1 抗体 (AA 4450-4500)
Quick Overview for FAT1 抗体 (AA 4450-4500) (ABIN7450240)
抗原
See all FAT1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 4450-4500
-
原理
- Rabbit anti-FAT1 Antibody, Affinity Purified
-
纯化方法
- Affinity Purified
-
免疫原
- Between AA 4450 and 4500
-
亚型
- IgG
-
-
-
-
应用备注
-
IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
-
限制
- 仅限研究用
-
-
-
浓度
- 1000 μg/mL
-
缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
有效期
- 12 months
-
-
- FAT1 (FAT Tumor Suppressor Homolog 1 (FAT1))
-
别名
- FAT1
-
背景
- Background: Protocadherin Fat 1 is an ortholog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. FAT1 is a member of the cadherin superfamily, a group of integral membrane proteins characterized by the presence of cadherin-type repeats. In addition to containing 34 tandem cadherin-type repeats, FAT1 has five epidermal growth factor (EGF)-like repeats and one laminin A-G domain. FAT1 is expressed at high levels in a number of fetal epithelia. Its product probably functions as an adhesion molecule and/or signaling receptor, and is likely to be important in developmental processes and cell communicatio [taken from NCBI Entrez Gene (Gene ID: 2195)].
-
基因ID
- 2195
-
NCBI登录号
- NP_005236
-
UniProt
- Q14517
抗原
-