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CSK 抗体 (AA 400-450)

This anti-CSK antibody is a 兔多克隆 antibody detecting CSK in WB 和 IP. Suitable for 人和小鼠.

产品编号 ABIN7450141

发货至: 中国

Quick Overview for CSK 抗体 (AA 400-450) (ABIN7450141)

抗原

See all CSK 抗体

CSK (C-Src tyrosine Kinase (CSK))

适用

105
57
47
4
4
3
2
2
2
2
1
1
1

人, 小鼠

宿主

兔

克隆类型

多克隆

标记

56
7
6
5
3
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1

This CSK antibody is un-conjugated

应用范围

96
41
26
26
18
16
13
9
9
6
6
1
1
1

Western Blotting (WB), Immunoprecipitation (IP)

Discover our top product CSK Primary Antibody

抗原表位
18

16

8

8

7

7

6

5

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 400-450

原理

Rabbit anti-CSK Antibody, Affinity Purified

纯化方法

Affinity Purified

免疫原

Between AA 400 and 450

亚型

IgG
anti-C-Src tyrosine Kinase (CSK) (AA 1-100) antibody
CSK 适用: 人 WB, ELISA, IP, IHC (p), RNAi 宿主: 小鼠 Monoclonal 3A3 unconjugated

anti-C-Src tyrosine Kinase (CSK) (C-Term) antibody
Verified CSK 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated

anti-C-Src tyrosine Kinase (CSK) antibody
CSK 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated

anti-C-Src tyrosine Kinase (CSK) antibody
CSK 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 5F3 unconjugated

anti-C-Src tyrosine Kinase (CSK) (AA 243-438) antibody
CSK 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-C-Src tyrosine Kinase (CSK) (AA 325-416) antibody
CSK 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-C-Src tyrosine Kinase (CSK) (AA 67-101), (N-Term) antibody
CSK 适用: 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB50568 unconjugated

anti-C-Src tyrosine Kinase (CSK) (Ser280) antibody
CSK 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-C-Src tyrosine Kinase (CSK) (AA 330-450) antibody
CSK 适用: 人, 小鼠 WB, IP, ICC 宿主: 小鼠 Monoclonal CSK-04 unconjugated

anti-C-Src tyrosine Kinase (CSK) (AA 241-450) antibody
CSK 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

应用备注

IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000

限制

仅限研究用
浓度

1000 μg/mL

缓冲液

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C

有效期

12 months
抗原

CSK (C-Src tyrosine Kinase (CSK))

别名

CSK

背景

Background: C-Src kinase (CSK) is a non-receptor tyrosine-protein kinase that plays an important role in the regulation of cell growth, differentiation, migration and immune response. CSK phosphorylates tyrosine residues located in the C-terminal tails of Src-family kinases (SFKs) including LCK, SRC, HCK, FYN, LYN or YES1. Upon tail phosphorylation, Src-family members engage in intramolecular interactions between the phosphotyrosine tail and the SH2 domain that result in an inactive conformation. To inhibit SFKs, CSK is recruited to the plasma membrane via binding to transmembrane proteins or adapter proteins located near the plasma membrane. CSK suppresses signaling by various surface receptors, including T-cell receptor (TCR) and B-cell receptor (BCR) by phosphorylating and maintaining inactive several positive effectors such as FYN or LCK [taken from the Universal Protein Resource (UniProt) P41240].

基因ID

1445

NCBI登录号

NP_004374

UniProt

P41240

途径

TCR Signaling, EGFR Signaling Pathway, Cell-Cell Junction Organization, CXCR4-mediated Signaling Events

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