MCAM 抗体 (AA 600-650)
Quick Overview for MCAM 抗体 (AA 600-650) (ABIN7450088)
抗原
See all MCAM 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 600-650
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原理
- Rabbit anti-CD146 Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- Between AA 600 and 650
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亚型
- IgG
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应用备注
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- MCAM (Melanoma Cell Adhesion Molecule (MCAM))
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别名
- CD146
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背景
- Background: CD146 plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. CD146 could be an adhesion molecule active in neural crest cells during embryonic development. CD146 acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration [taken from the Universal Protein Resource (UniProt) P43121].
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基因ID
- 4162
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NCBI登录号
- NP_006491
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UniProt
- P43121
抗原
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