ATG13 抗体 (AA 450-500)
Quick Overview for ATG13 抗体 (AA 450-500) (ABIN7449999)
抗原
See all ATG13 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 450-500
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原理
- Rabbit anti-ATG13/KIAA0652 Antibody, Affinity Purified
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预测反应
- X. tropicalis,Bovine,Orangutan,Chimpanzee
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纯化方法
- Affinity Purified
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免疫原
- Between AA 450 and 500
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亚型
- IgG
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应用备注
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- ATG13 (Autophagy Related 13 (ATG13))
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别名
- ATG13/KIAA0652
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背景
- Background: Autophagy-related protein 13 (ATG13) is an autophagy factor required for autophagosome formation and mitophagy. It is a target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, ATG13 plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation [taken from the Universal Protein Resource (UniProt) O75143].
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基因ID
- 9776
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UniProt
- O75143
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途径
- PI3K-Akt Signaling, Autophagy
抗原
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