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ATF6 抗体 (AA 125-175)

The 兔 多克隆 anti-ATF6 antibody is suitable to detect ATF6 in samples from 人. It has been validated for WB 和 IP.
产品编号 ABIN7449998
发货至: 中国
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北京 101111
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Quick Overview for ATF6 抗体 (AA 125-175) (ABIN7449998)

抗原

See all ATF6 抗体
ATF6 (Activating Transcription Factor 6 (ATF6))

适用

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  • 4
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  • 1
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宿主

  • 96
  • 11
  • 1

克隆类型

  • 86
  • 22
多克隆

标记

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This ATF6 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP)
  • 抗原表位

    • 16
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    AA 125-175

    原理

    Rabbit anti-ATF6 Antibody, Affinity Purified

    纯化方法

    Affinity Purified

    免疫原

    Between AA 125 and 175

    亚型

    IgG
  • 应用备注

    IP: 2 - 10 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    限制

    仅限研究用
  • 浓度

    1000 μg/mL

    缓冲液

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    ATF6 (Activating Transcription Factor 6 (ATF6))

    别名

    ATF6

    背景

    Background: Activating transcription factor 6 (ATF6) is a transcription factor that activates target genes for the unfolded protein response (UPR) during endoplasmic reticulum (ER) stress. Although it is a transcription factor, this protein is unusual in that it is synthesized as a transmembrane protein that is embedded in the ER. It functions as an ER stress sensor/transducer, and following ER stress-induced proteolysis, it functions as a nuclear transcription factor via a cis-acting ER stress response element (ERSE) that is present in the promoters of genes encoding ER chaperones. This protein has been identified as a survival factor for quiescent but not proliferative squamous carcinoma cells [taken from NCBI Entrez Gene (Gene ID: 22926)].

    基因ID

    22926

    NCBI登录号

    NP_031374

    UniProt

    P18850

    途径

    ER-Nucleus Signaling, Unfolded Protein Response
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