CUL9 抗体 (AA 1-50)
Quick Overview for CUL9 抗体 (AA 1-50) (ABIN7449782)
抗原
See all CUL9 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-50
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原理
- Rabbit anti-PARC/H7-AP1 Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 1 and 50
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亚型
- IgG
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应用备注
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IP: 2 - 10 μg/mg lysate
WB: 1:1,000 - 1:5,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- CUL9 (Cullin 9 (CUL9))
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别名
- PARC/H7-AP1
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背景
- Background: PARC is a member of the cullin family of proteins that act as scaffolds to bring together ubiquitin E3 ligases, E2 conjugating enzyme, and substrate proteins to mediate the ubiquitination of substrate proteins. PARC is highly homologous to and can form heterodimers with CUL7 (cullin 7). PARC/H7 interacts with p53 and was initially thought to have a role in the sequestration of p53 to the cytoplasm. Recent studies demonstrate that PARC may not influence p53 function or localization, but rather p53 may serve to regulate PARC/H7-AP1 function.
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基因ID
- 23113
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NCBI登录号
- NP_055904
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UniProt
- Q8IWT3
抗原
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