DAB2 抗体 (AA 275-325)
Quick Overview for DAB2 抗体 (AA 275-325) (ABIN7449708)
抗原
See all DAB2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 275-325
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原理
- Rabbit anti-Dab2 Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- Between AA 275 and 325
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亚型
- IgG
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应用备注
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IP: 2 - 10 μg/mg lysate
WB: 1:1,000 - 1:5,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- DAB2 (Disabled Homolog 2, Mitogen-Responsive phosphoprotein (Drosophila) (DAB2))
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别名
- Dab2
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背景
- Background: Disabled homolog 2 (Dab2) is an adapter protein that functions as a clathrin-associated sorting protein (CLASP) required for clathrin-mediated endocytosis of selected cargo proteins. Dab2 can bind and assemble clathrin, and binds simultaneously to phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) and cargos containing non-phosphorylated NPXY internalization motifs, such as the LDL receptor, to recruit them to clathrin-coated pits [taken from the Universal Protein Resource (UniProt) P98082].
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基因ID
- 1601
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NCBI登录号
- NP_001334
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UniProt
- P98082
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process
抗原
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