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Neurofibromin 1 抗体 (C-Term)

The 兔 多克隆 anti-Neurofibromin 1 antibody is suitable to detect Neurofibromin 1 in samples from 人 和 小鼠. It has been validated for WB 和 IP.
产品编号 ABIN7449677
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Neurofibromin 1 抗体 (C-Term) (ABIN7449677)

抗原

See all Neurofibromin 1 (NF1) 抗体
Neurofibromin 1 (NF1)

适用

  • 67
  • 53
  • 36
  • 2
  • 2
  • 2
  • 2
  • 1
人, 小鼠

宿主

  • 75
  • 8

克隆类型

  • 73
  • 10
多克隆

标记

  • 31
  • 5
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Neurofibromin 1 antibody is un-conjugated

应用范围

  • 39
  • 39
  • 28
  • 23
  • 15
  • 13
  • 10
  • 9
  • 8
  • 5
  • 5
  • 1
  • 1
Western Blotting (WB), Immunoprecipitation (IP)
  • 抗原表位

    • 15
    • 15
    • 15
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    原理

    Rabbit anti-NF1 Antibody, Affinity Purified

    预测反应

    Rat

    纯化方法

    Affinity Purified

    免疫原

    between AA 2760 and C-term

    亚型

    IgG
  • 应用备注

    IP: 2 - 10 μg/mg lysate

    WB: 1:1,000 - 1:10,000

    限制

    仅限研究用
  • 浓度

    1000 μg/mL

    缓冲液

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    Neurofibromin 1 (NF1)

    别名

    NF1

    背景

    Background: Inactivating mutations in NF1 (neurofibromin 1) result in neurofibromatosis type I (NF1) which is characterized by Schwann cell neurofibromas, café-au-lait spots, and benign lesions of the iris. At the cellular level, NF1 functions as a negative regulator of Ras activity. Loss of NF1 leads to increased levels of active Ras-GTP which is important for the formation and maintenance of Schwann cell tumors.

    基因ID

    4763

    NCBI登录号

    NP_000258

    UniProt

    P21359

    途径

    cAMP Metabolic Process, Regulation of long-term Neuronal Synaptic Plasticity
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