Ataxin 1 抗体 (AA 350-400)
Quick Overview for Ataxin 1 抗体 (AA 350-400) (ABIN7449649)
抗原
See all Ataxin 1 (ATXN1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 350-400
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原理
- Rabbit anti-Ataxin-1 Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 350 and 400
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亚型
- IgG
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应用备注
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IP: 10 μg/mg lysate
WB: Not recommended. Use rabbit anti-Ataxin-1 antibody A302-292A.
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- Ataxin 1 (ATXN1)
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别名
- Ataxin-1
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背景
- Background: Defects in ataxin-1 are the cause of spinocerebellar ataxia type 1 (SCA1), also known as olivopontocerebellar atrophy I (OPCA I or OPCA1). Patients show progressive incoordination of gait and often poor coordination of hands, speech and eye movements, due to cerebellum degeneration with variable involvement of the brainstem and spinal cord. SCA1 is caused by expansion of a CAG repeat in the coding region of the ataxin-1 gene. Longer expansions result in earlier onset and more severe clinical manifestations of the disease. Ataxin-1 binds RNA in vitro and may be involved in RNA metabolism [taken from the Universal Protein Resource (UniProt) P54253].
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基因ID
- 6310
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NCBI登录号
- NP_000323
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UniProt
- P54253
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途径
- Synaptic Membrane
抗原
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