SKP2 抗体 (AA 50-100)
Quick Overview for SKP2 抗体 (AA 50-100) (ABIN7449624)
抗原
See all SKP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 50-100
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原理
- Rabbit anti-SKP2 Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 50 and 100
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亚型
- IgG
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应用备注
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IP: 10 - 15 μg/mg lysate
WB: Not recommended. Use rabbit anti-SKP2 antibody ABIN7450734.
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- SKP2 (S-Phase Kinase-Associated Protein 2 (SKP2))
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别名
- SKP2
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背景
- Background: S-phase kinase-associated protein 2 (SKP2) is a member of the F-box family of proteins. It is the substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and transcription. SKP2 specifically recognizes phosphorylated CDKN1B/p27kip and is involved in regulation of G1/S transition [taken from the Universal Protein Resource (UniProt) Q13309].
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基因ID
- 6502
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NCBI登录号
- NP_005974
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UniProt
- Q13309
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途径
- Mitotic G1-G1/S Phases
抗原
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