STK26/MST4 抗体 (AA 300-350)
Quick Overview for STK26/MST4 抗体 (AA 300-350) (ABIN7449611)
抗原
See all STK26/MST4 (MST4) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 300-350
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原理
- Rabbit anti-MST4/MASK Antibody, Affinity Purified
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预测反应
- Mouse
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纯化方法
- Affinity Purified
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免疫原
- between AA 300 and 350
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亚型
- IgG
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应用备注
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IP: 1 - 4 μg/mg lysate
WB: Not recommended. Use rabbit anti-MST4/MASK antibody ABIN7452894.
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- STK26/MST4 (MST4) (Serine/threonine-Protein Kinase MST4 (MST4))
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别名
- MST4/MASK
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背景
- Background: MST4/STK24 is a member of the sterile 20 (Ste20)-like kinase family that acts upstream of mitogen-activated protein kinase (MAPK) pathways and regulates c-Jun N-terminal kinase (JNK), p38 and extracellular signal-regulated kinase (ERK). Ste20-like kinases are involved in a variety of cellular processes which include gene transcription, stress responses, cytoskeletal organization and apoptosis. In response to apoptotic signals, MST4/MASK is cleaved by caspase-3 and mediates apoptosis. MST4/MASK has been shown to influence cell growth and transformation by modulating ERK (extracellular signal-regulated kinase) signaling and may play a role in prostrate cancer. MST4/MASK may also play a role in cell motility.
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基因ID
- 51765
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NCBI登录号
- NP_057626
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UniProt
- Q9P289
抗原
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