HRPT2 抗体 (AA 250-300)
Quick Overview for HRPT2 抗体 (AA 250-300) (ABIN7449603)
抗原
See all HRPT2 (CDC73) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 250-300
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原理
- Rabbit anti-Parafibromin Antibody, Affinity Purified
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预测反应
- Rat
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纯化方法
- Affinity Purified
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免疫原
- between AA 250 and 300
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亚型
- IgG
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应用备注
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IP: 1 - 4 μg/mg lysate
WB: 1:5,000 - 1:20,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- HRPT2 (CDC73) (Parafibromin (CDC73))
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别名
- Parafibromin
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背景
- Background: Parafibromin, also known as HRPT2 (hyperparathyroidism 2 protein), has been identified as a tumor suppressor that is associated with hyperparathyroidism-jaw tumor syndrome, an autosomal dominant disease characterized by hyperparathyroidism due to parathyroid tumors and ossifying fibromas of the mandible and maxilla. Parafibromin is a component of the PAF1 complex that associates with RNA polymerase II and plays a role in mRNA 3'-end processing and transcription elongation. Parafibromin has been demonstrated to function as an inhibitor of the cell cycle.
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基因ID
- 79577
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NCBI登录号
- NP_078805
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UniProt
- Q6P1J9
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途径
- Cellular Response to Molecule of Bacterial Origin, Stem Cell Maintenance
抗原
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