MTA2 抗体 (AA 500-550)
Quick Overview for MTA2 抗体 (AA 500-550) (ABIN7449600)
抗原
See all MTA2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 500-550
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原理
- Rabbit anti-MTA2 Antibody, Affinity Purified
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预测反应
- Mouse
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纯化方法
- Affinity Purified
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免疫原
- between AA 500 and 550
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亚型
- IgG
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应用备注
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IP: 1 - 4 μg/mg lysate
WB: 1:5,000 - 1:15,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- MTA2 (Metastasis Associated 1 Family, Member 2 (MTA2))
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别名
- MTA2
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背景
- Background: MTA2 (metastasis-associated protein 2) is a component of the NuRD (nucleosome remodeling and histone deacetylation) complex. MTA2 is highly similar to MTA1 and was identified as a factor differentially expressed in a carcinoma cell line. MTA2 can repress p53-dependent transcriptional activation by enhancing its deacetylation. MTA1 has also been shown to function as a corepressor for ligand-induced estrogen receptor (ER) transactivation. As part of the NuRD complex MTA2 represses ERalpha transactivation activity by modulating the acetylation status of ERalpha.
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基因ID
- 9219
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NCBI登录号
- NP_004730
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UniProt
- O94776
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途径
- Chromatin Binding
抗原
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